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Months 4-6: Optimization and Intensification (As Described Above) The second quarter deepens therapeutic effects and allows for protocol refinement based on ongoing response patterns

TNF produces inflammation by chemokines, cytokines, metalloproteinases, prostaglandin E2, and adhesion molecules

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Moreover, although many natural compounds share neuroprotective mechanismssuch as antioxidant and anti-inflammatory effectstheir actions are not necessarily redundant (Zhang et al., 2022)

Some patients may use them in combination under physician guidance, but cycling principles still apply