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Since synergy demands a higher standard than simple overlap, its evaluation requires comparisons between combinations and individual peptides, standardized injury models, and predefined evaluation criteria (migration assays, histology, collagen organization, vascular markers, inflammatory markers, and functional metrics)

Monitoring and follow-up: practical guidance For patients starting injections, baseline labs should include B12 level, complete blood count and, when indicated, renal function

doi: 10.3390/ijms19071987

These effects typically resolve within days as the body adjusts