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In this regard, as 15LO1 increased, GPX4 expression concomitantly increased to balance the high 15LO1 activity (Figure 2C)

As a result of overexpression GGCT, not only did the level of glutamate m + 5 decrease, but also the levels of downstream metabolites such as -KG m + 5, succinate m + 4, fumarate m + 4 and malate m + 4 in the TCA cycle were affected (Fig

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Glutathione is a vital key to health, and modern adults simply no longer make enough

Many state-of-art tools developed lack the efficiency to precisely measure the in vivo dynamics