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Such inflammatory cytokines may either cross the blood-brain-barrier, especially if it is damaged, or be produced in situ by reactive astrocytes and microglia (137)

PLoS Biol 16(5):e2006203 Finkel T (2011) Signal transduction by reactive oxygen species

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5B) was most likely due to its flux into NADP(H) production, where NADPH is required by xenobiotic detoxification enzymes for the metabolism of Dox

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