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Figure 6 Number of studies analyzed that confirm the relationship between the use of EC and the consumption of conventional cigarettes and other substances DISCUSSION The present study posed the following research question: What are the risk and protective factors for e-cigarette use among adolescents, its association with tobacco and other substance use, and the evidence of its use as a smoking cessation strategy?

Previous studies have shown that, compared with never-smokers, current smokers have an OR of 3.51 (95% CI: 3.083.99), and former smokers have an OR of 2.89 (95% CI: 2.633.17) for COPD risk, with smoking duration being a key factor (33, 34)

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As consumers in these regions become more aware of alternative smoking options, disposable e-cigarettes present a viable solution