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In line with evidence accrued in patients with T2D, incretin-based therapies produced a favorable effect on traditional cardiovascular risk factors, such as lipids and blood pressure, and even reduced the risk of major cardiovascular events and heart failure-related events in individuals with obesity, as recently demonstrated for the first time in the SELECT trial with semaglutide 2.4 mg once-weekly

FLOW - kidney-outcomes benefit at 1.0 mg

This is the first stage where a before-and-after comparison would show a noticeable difference

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Unless the reconstituted peptides stability requirements mandate refrigerated or frozen storage, in which case follow the reconstituted compounds specific storage temperature guidance