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Total clearance from steady state takes closer to 30 to 35 days rather than the 25 days calculated from a single dose

In the FAS population, the median GSH concentration appeared artificially higher in the placebo (459 mol/L) than in the NAC (402 mol/L) group, due to imputation method for missing values (15%-NAC and 5%-Placebo) (Fig

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In these roles, NAC may be a useful monotherapy or augmentation strategy for psychiatric disorders related to oxidative stress (e.g., schizophrenia and bipolar disorder) and/or psychiatric syndromes characterized by impulsive/compulsive symptoms (e.g., trichotillomania, nail biting, pathological hair pulling, substance misuse, and gambling)

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