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It is important to elucidate the mechanisms regulating CRPC, specifically focusing on the molecular alterations that participate in the activation of androgen receptor-independent pathways

First, the overall gene expression patterns were visualized using principal component analysis (PCA), which revealed evident transcriptomic differences among the PBS, P-Mn@mHSA, and P-Mn/TI@mHSA groups, with no outlier samples detected (Fig

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Research has identified both genetic and environmental factors, especially those involving fetal and early life development, in describing this complex condition