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Compared with the COPD rats treated with NAC + oe-VWF + sh-NC, levels of IgG, IgA, and IgM reduced in serum of COPD rats treated with NAC + oe-VWF + sh-p38 MAPK (Fig

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doi: 10.1016/j.plefa.2018.04.003 65

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the main factors that are generally associated with elevations of homocysteine are nutritional deficiency, particularly related to folate metabolism, mutations of the enzymes MTHFR and CBS (Aguilar)