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Treatment courses often extend for at least three to six months before meaningful cosmetic changes might be appreciated, and continued application may be required to maintain any gains

[10] Davies, Melanie J

Furthermore, simvastatin treatment combined with PD-L1 antibody could not only improve the prognosis of the intrahepatic inoculation HCC model but also achieve satisfactory therapeutic efficacy in model of advanced HCC (Yu et al., 2022)