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Beyond direct suppression, strategic combination therapies can redirect cellular responses

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This is due to their potential for some serious side effects, such as an allergy, although they occur very rarely

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Vitamin C functions optimally in an acidic environment (pH 3.5 or lower), while retinol prefers a neutral to slightly alkaline environment (pH 6-7)

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and Onyebuchi Okosieme for their contribution to the peer review of this work

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