ROS can mediate the onset of cellular death, including conventional apoptosis (i.e., the mitochondrial pathway, the death receptor pathway, and the endoplasmic reticulum pathway), cellular scorched death, and iron death
The closest structural relative was found to be human CLIC1 (PDB code 1K0O), in which 156 C could be aligned with a root-mean-square deviation (RMSD) value of 0.93 , followed by GSTO1 from Homo sapiens (PDB code 3LFL) (122 aligned C with an RMSD of 2.07 ) and the putative stringent starvation protein A from Burkholderia cenocepacia (PDB code 4QQ7) (122 aligned C with an RMSD of 2.14 ) 12,15
In: Progress in Mountain Medicine and High Altitude Physiology
Antioxidants were also used as adjuvant therapies in combination with ovulation induction agents in infertile patients with PCOS (146)
In feline medicine, NACs antioxidant properties may also contribute to reduced susceptibility to feline coronavirus infection, a disease in which oxidative stress and disruption of redox balance are known pathogenic factors (Izquierdo-Alonso et al., 2022)