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Only under strict medical care

In a separate set of experiments performed in the other participating laboratory in Turin with the Palo Alto parasite strain, similar data were obtained, showing that the invasion rate of GR-deficient RBCs was as high as that of control RBCs (30% parasitemia at 19 h after inoculation with 6.4% schizonts), and regular development into trophozoites was observed on day 2 (30% parasitemia)

Eur J Haematol 110:490497

Moreover, overexpression of GspD resulted in a doubling of the AEP trails for cells grown in high levels of copper (32 17 trails/cell

The UK regulator recommends that in adults weighing less than 50 kg, clinical judgement should be employed when prescribing oral paracetamol as these patients may be at increased risk of hepatotoxicity but does not specify a dose reduction