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Nephrotoxicity of lysine was also demonstrated in dogs infused with lysine hydrochloride [125]

HFpEF exhibits more complexity and has more associated-comorbidities including hypertension compared to HFrEF, and systemic inflammation and its-induced metabolic injury are closely associated with the pathogenesis of HFpEF

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10.1136/bmj.1.5698.716 150 HebertL

275 PrP Sc and other prion-like polypepetides have the interesting properties of being infectious and able to induce the generation of more prion particles when seeded from one CNS region to another or from even from one individual to another either by ingestion via the diet, or via implantation into the CNS for example from surgical instruments or tissue grafts