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However, some individuals may experience local irritation at the injection site, mild gastrointestinal disturbances, or, rarely, allergic reactions
For instance, the Vitamin B12 deficiency is also associated with higher body weight and fat mass, according to a 2023 study
[DOI] [PMC free article] [PubMed] [Google Scholar] 243.Nguyen TB, Louie SM, Daniele JR, Tran Q, Dillin A, Zoncu R, et al
Cardiovascular (Heart and Blood Vessel) Complications In rare but serious cases, B12 replacement can lead to heart and blood vessel problems: Shortness of breath Peripheral edema (swelling in legs and arms) Rapid weight gain Pulmonary edema (fluid in lungs) Congestive heart failure (heart cannot pump effectively) Blood clots in vessels These complications arise from increased blood volume, thicker blood, and sudden changes in how hard the heart needs to work
