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The new nationwide Tobacco 21 measure continues momentum that began with localities and states across the U.S

In the late 1990s, the tobacco industry was at the center of debate, controversy, and subsequent state lawsuits over addictive substances and cancer-causing agents contained in cigarettes

The decision is estimated to cost the company about 205.8 billion won ($174 million) in lost sales, amounting to around 3.9 percent of the company's overall sales revenue for last year

The two flavones showed a potent cytotoxic effect against cancerous cell lines, 8formyl7hydroxy6,4dimethoxyflavone against CCRFCEM (human lymphoblastic leukemia) and P388D1 (murine macrophagelike lymphoma) cell lines, with IC50 values of 2.24 0.32 g/mL

Centers for Diseases Control and Prevention