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Adding vitamin D (if you're deficient) and an omega-3 with EPA and DHA covers the metabolic and inflammatory bases

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Immune cells and senescent cells contribute to aging-associated inflammation 3,4,5,6

After treatment withdrawal (V4), this response contracted selectively, with IL-17A (p = 0.046) and IL-33 (p = 0.008) declining significantly, while other mediators showed partial but non-significant attenuation