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10.1016/j.biomaterials.2012.12.009 [DOI] [PubMed] [Google Scholar] Charlier E., Deroyer C., Ciregia F., Malaise O., Neuville S., Plener Z., et al

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Over half of participants lost 20% or more of body weight

Protein is expressed in all major organs after intravenous infusion of mRNA-lipid nanoparticles in swine

Sporadic use or frequent missed doses does not provide adequate assessment of individual response