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This is crucial in high-fat environments, like brain tissue rich in lipids, where unchecked peroxidation could lead to neurological issues
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Understanding this is the foundation for understanding why dosing is not a one-size-fits-all figure: the molecule behaves differently from the compounds people often group it with
However, although erastin shows antitumor effects, it has not entered clinical trials because it is poorly soluble in water, and its metabolism in vivo is unpredictable
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