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Bioorg Med Chem Lett 22:18221826 Eaton JK, Furst L, Ruberto RA, Moosmayer D, Hilpmann A, Ryan MJ, Zimmermann K, Cai LL, Niehues M, Badock V, Kramm A, Chen S, Hillig RC, Clemons PA, Gradl S, Montagnon C, Lazarski KE, Christian S, Bajrami B et al (2020) Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles

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She was a 57-year-old African American female (normally I wouldnt bother to designate a patients race, but this was relevant, as youll soon see) who complained of debilitating muscle cramps

In addition, a slew of emerging classes of TXNRD inhibitors have surfaced, encompassing diverse agents such as natural products, metal complexes, and nitro (hetero) aromatic compounds [240]

Chronic kidney disease and poor outcomes in ischemic stroke: is impaired cerebral autoregulation the missing link