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The exometabolome also showed significant changes depending on the presence of albumin (Fig

Cytokine storm, in tandem with lymphopenia, lymphocyte dysfunction, and granulocyte/ monocyte abnormalities, could increase the disease severity of COVID-19 222

There is also a very safe profile (lethal dose (LD1) could be not achieved) [84], a point recently confirmed in a large study conducted by Xu and collaborators [85]

In addition, manufacturers need to undergo regular audits by regulatory authorities to ensure that their production facilities and quality management systems comply with GMP requirements