This difference allows lysine to often act as a general acidbase catalyst in enzyme active sites, or to participate in reactions through nucleophilic attack (such as forming a Schiff base)
Cutsem EV, Cuyle PJ, Huijberts S, Yaeger R, Schellens JHM, Elez E, Tabernero J, Fakih M, Montagut C, Peeters M, Desai J, Yoshino T, Ciardiello F, Wasan HS, Kopetz S , Maharry K, Christy-Bittel J, Gollerkeri A, Grothey A
The BTB domain binds CUL3 and is used to link to E3 ubiquitin ligase, the IVR domain regulates cysteine residue activity, and the Kelch repeat domain is mainly responsible for linking to Nrf2 (Fig
Biochemical Journal, 476(24), 38173834
She doesnt believe in unnecessary medications or procedures