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Future investigations should focus on understanding the role of NLRP3 at different phases of APAP-induced liver injury, its activation in various cell types, including hepatocytes and Kupffer cells, and validating its involvement in liver damage in multiple animal models through comparative analyses

mansoni -derived apoptosis inducing factor, seemingly exert their immunomodulatory properties by direct targeting of T cells

Then we evaluated the effect of iNOS inhibition on the parasite burden and tissue pathology

Li YF, Dong Z, Chen C, et al