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However, during apoptosis, the mitochondrial membrane potential is lost and the mitochondrial permeability transition pore (MPTP) remains open, allowing TMRE to escape into the cytoplasm, resulting in a significant reduction of orange-red fluorescence within the mitochondria [44]

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By the time he passed away in 2023, GHK-Cu had been cited in studies on skin, lungs, bone, and the nervous system