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The review examined how Dihexa and related compounds enhance HGF/c-Met signaling, promoting downstream pathways involved in synaptogenesis, neurite outgrowth, and neuronal survival

38 There is evidence that genetic variability or absence of OATP1B1/1B3 function, as seen in RS, can substantially increase plasma concentrations of drugs including statins, ezetimibe, angiotensin II receptor blockers, methotrexate, mycophenolic acid, cyclosporin A, rifampicin, thiazolidinediones, glinides, antiretrovirals, antihistamines, and several anticancer agents (Table 2)

are Virginia Murchison Linthicum Scholars in Medical Research at UTSW

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When I was developing the scheme to synthesize my compound, I found that process very challenging, she admits