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The nicotine or heat from the vapor increases the risk of gum recession and exposes the underlying root structure

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The researchers identified three studies, in 1498 people, that compared nicotine-containing electronic cigarettes with nicotine replacement therapy given as patches or gum

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In the body, flavin-containing monooxygenase is responsible for the oxidation of nicotine to nicotine N-oxide, but this compound can also form when nicotine is simply in contact with air or light