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It has been reported that the inhibition of PGC-1 decreases the glycolytic pathway, increases ROS generation, and impairs cell proliferation

(2018, October 25)

Statistical analyses were performed in R v4.1.2 (37) using libraries nlme (Reference Pinheiro and Bates38) , multcomp (Reference Hothorn, Bretz and Westfall39) , lme4 and ggplot2 (Reference Wickham40)