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The control group: included 30 patients who received a placebo in the form of glucose 5% for one month before the cardiac surgery

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Essential for maintaining the efficiency of life-sustaining chemical reactions, metabolic homeostasis relies on a balance between anabolic and catabolic pathways, the latter being critical for energy production (Pflug et al., 2021)

A 2019 review in Aging Cell noted that metformin reduced circulating TNF-alpha by 17% and IL-6 by 24% in a pooled analysis of 664 patients with type 2 diabetes across four randomized controlled trials [9]

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