Why this trial matters : First effective gene therapy for EB Meaningfully improves quality of life and patient outcomes Drug Approvals as a Signal: 2025 Showed Real Late-Stage Productivity The FDAs 2025 novel drug approvals, alongside pivotal trialdriven cancer approvals, point to real late-stage productivity rather than incremental gains
Stahr PL, Grewal R, Eckert GP, Keck CM
10.1038/mp.2017.144 Summary Keywords glutamate, neuromodulation, TMS (repetitive transcranial magnetic stimulation), direct current stimulation (tDCS), photo-biomodulation therapy, treatment-resistant depression, depression, mini review Citation Khoodoruth MAS, Estudillo-Guerra MA, Pacheco-Barrios K, Nyundo A, Chapa-Koloffon G and Ouanes S (2022) Glutamatergic System in Depression and Its Role in Neuromodulatory Techniques Optimization
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[27] These peptides are considered exorphins, as they have morphine-like effects on the brain