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The most common adverse effects include nausea, vomiting, diarrhea, constipation, decreased appetite, and abdominal discomfort

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Additionally, RSV is a known activator of sirtuin 1 (SIRT1), a nicotinamide adenine dinucleotide (NAD + )-dependent deacetylase involved in cellular stress resistance, metabolic regulation, and longevity

Clinical data showed that participants who skipped titration steps or escalated too quickly experienced nearly double the rate of gastrointestinal adverse events