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Obesity-related asthma individuals have worsened asthma severity [25, 26], symptom burden [19, 27], the highest healthcare utilization rates [28, 29], reduced effectiveness of conventional therapies [30, 31], and different metabolic signatures [32], compared to individuals that are normal-weight and diagnosed with asthma

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This intriguing compound has garnered significant interest in the fields of medical research and sports medicine due to its purported therapeutic effects

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The weight loss effect depends specifically on AMY1R and AMY3R activation, as confirmed by a study in eBioMedicine that showed cagrilintide lowers body weight through these specific receptor subtypes in the brainstem