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Acknowledgements We thank all the members of Professor Ah-Ng Tony Kongs laboratory for their invaluable discussion in the preparation of this manuscript

The highest antibody (IgG) serum levels were seen in the following distribution of subjects studied: (8) Mean values for half-life were between 17.5 and 25 days, with the shortest being 5.9 days and the longest 35 days.(8) Cases of type B hepatitis are rarely seen following exposure to HBV in persons with preexisting anti-HBs