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In laboratory and preclinical studies, GHK-Cu has been reported to stimulate collagen synthesis in dermal fibroblasts, support production of glycosaminoglycans and elastin, and accelerate epithelialization in wound models

This Review outlines the need for new therapeutic agents for patients with acromegaly, reviews clinical trial data of investigational agents and considers how these therapies might best be integrated into clinical practice

yet, most peptides that were originally considered to be exclusively synthesized in the periphery are now also known to be generated in the central nervous system (CNS)

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