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In addition to mitochondrial and iron-derived ROS, impaired nitric oxide (NO) signaling constitutes another pivotal source of redox disruption in PCOS

Passos IC, Mwangi B, Vieta E, Berk M, Kapczinski F

Current evidence does not support the use of B12 as a weight loss intervention, and B12 products have no licensed indication for weight loss in the UK

Vitamin C regenerates oxidized glutathione back to its active form, supports collagen synthesis, suppresses excess melanin formation, and enhances overall antioxidant capacity

Challenges in tackling energy expenditure as obesity therapy: from preclinical models to clinical application