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Growth Hormone Sensitization: Increases GH receptor expression and enhances JAK2/STAT signaling (PMC6271067)

The clinical trial most often cited is Leyden and colleagues' 2002 randomized 12-week trial of a GHK-Cu facial and eye cream in 71 women with photoaged skin [4]

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(Midi does not prescribe this or other unapproved peptides.) What the science says: Theres promising preclinical (aka animal or lab) data on MOTS-c, and early research suggests that MOTS-c may improve metabolism by activating the AMPK pathway and help reverse age-related insulin resistance