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In current studies, the mechanisms involved in UA induced cardiomyocytic injury include ROS/CaMKII/Parkin pathway (Zhang et al., 2020), and calpain-1 and endoplasmic reticulum stress (Yan et al., 2018)

As evaluated, pFeSAN exhibited a long-term stability in water, acetate buffer (pH 4.0) and cell culture medium without the significant changes of the average hydrodynamic diameters during 1-week co-incubation (Supplementary Fig

Ormazabal V, Nair S, Elfeky O, Aguayo C, Salomon C, Zuiga FA

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A randomized, single-blind trial was performed by Zhong and colleagues [122] to evaluate the clinical efficacy and safety of ALA in 17 severely ill COVID-19 patients (mean age 63 years) admitted to JinYinTan Hospital in Wuhan