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Moreover, iron-induced oxidative damage compromises the BBB, allowing harmful substances to infiltrate the brain and intensify neuroinflammation, creating a vicious cycle of neuronal dysfunction and degeneration [85,101,102]
[PMC free article: PMC3161301] [PubMed: 21775755] (Among 460 patients with diabetic polyneuropathy treated with ALA [600 mg] or placebo once daily for 4 years, there were no differences in the primary outcomes between the two treatment groups while severe adverse events were more frequent with ALA [38% vs 28%]
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Every time you puncture the vial's septum with a needle, you risk introducing airborne contaminants
Hui Wang, Qi Feng, Yang Yang, Dongwei Liu, Bin Zheng and Shiyang Li contributed to the writing of the manuscript
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