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Low iron levels are common, especially in certain subsets of the population

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Moreover, milk thistle has been shown to protect against glutathione depletion caused by toxins, such as alcohol and certain medications

The global sensitivity analysis also confirmed the importance of the redox cycle between SQ . and H 2 Q ( R 4 ), showing that the reverse rate constant, k m4 (SQ . reformation), was the second most sensitive (main interactions) with respect to model OCR and therefore ROS production, suggesting auto-oxidation is an essential part of the doxorubicin redox mechanism

J Neurochem 61: 16721676