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Over time, this cellular protection can translate into improved physical stamina, a higher threshold for exertion, and a reduction in the severity of post-exertional crashes

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Consider allergy or mast-cell evaluation when Hives, swelling or wheezing are prominent Symptoms occur without a clear food-histamine relationship Multiple environmental or medication triggers are present Episodes are systemic or severe Consider broader functional evaluation when Chronic diarrhea or malabsorption is present Food restriction keeps expanding Symptoms began after infection or major gastrointestinal disruption Diet and DAO provide only partial benefit A Practical Step-by-Step Plan Identify the dominant pattern Determine whether symptoms are mainly meal-related, allergy-related, mast-cell-like or associated with a persistent mood and behavioral pattern

Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder defined by the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) as observable behavioral deficits in social communication and social interaction across multiple contexts