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Their concern was that removing the regulated pathway did not stop patient demand

Signaling hormones like cortisol and adrenaline, regulated by our immune system, are used by our body to manage heart rate, blood pressure, and blood sugar, all of which can play a role in how much energy you have, your emotional intensity, and even your body weight

However, disruption of this equilibrium, for example through the blockage of mitochondrial fusion and fission, may lead to oxidative stress, mitochondrial dysfunction and metabolic alterations, and ultimately to the development of mitochondria-associated diseases (Xiao et al., 2021)

Reducing Oxidative Stress in the Gastrointestinal Tract Oxidative stress occurs when there aren't enough antioxidants to tackle the free radicals that can cause DNA and tissue damage, inflammation and more