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Tepezza, approved by the FDA in 2020, is used to treat Thyroid Eye Disease (TED), but some patients have reported hearing issues after its use

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However, this has not been attributed to the variables that are known to increase the level of augmentation, like lower heart rate, increased arterial stiffness, or higher systemic vascular resistance 24,26,36,48,49,62 In our study present smokers had higher upright AIx, and higher supine and upright AIx@75, in the absence of changes in BP, heart rate, ejection duration, PWV, and systemic vascular resistance that could explain an increase in AIx

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#1 He remained physically active well into his eighties