states where you can buy tobacco at 18 Updated map of minimum purchase/consumption age of in North America (Blue: 18; Pink: 19; Red: 21) (Source: https://en.m.wikipedia.org/wiki/Smoking_age) : r/MapPorn cigarette purchase age by state

I think we need to reconsider the way we discuss this with patients. Healio spoke with Bittoni about the study rationale, the implications of the results and plans for further research in this area

The self-medication hypothesis suggests that schizophrenia patients smoke, in part, to alleviate negative symptoms, dysphoric mood, and neurocognitive impairments by ameliorating a dysfunctional dopamine system.10 The addiction vulnerability hypothesis suggests that genetic and neurobiological factors associated with schizophrenia (ie, alterations in nicotinic acetylcholine receptors [nAChRs] and central dopamine systems) may predispose schizophrenia patients to nicotine addiction.11 Examining the effects of tobacco smoking on neurocognition in schizophrenia is crucial because it may help clarify the rationale for high consumption of tobacco products and inform treatment interventions

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Nicotine effects on brain include a rapid increase in dopamine levels, stimulating the brains reward centers and creating feelings of pleasure

The alternate title, which appeared on the magazine, was -- But Wait Till Next Week