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As illustrated in Additional file 1: Figure S1C, animals from both TAT and TAT-DAT NT did not differ in time spent in each duration (two-way ANOVA with repeated measures, F 1, 10 = 0.321, p = NS), suggesting that the differences in spontaneous alternation behavior were unlikely due to confounding factors such as anxiety

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Its mechanisms include modulation of neurotransmitter signaling that promotes slow-wave activity, reduction of nighttime cortisol and stress hormone interference with sleep architecture, and support for the timing and depth of the sleep cycle itself

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