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Sikiric, P., Skrtic, A., Gojkovic, S., Krezic, I., Zizek, H., Lovric, E., Sikiric, S., Knezevic, M., Strbe, S., Milavic, M., Kokot, A., Blagaic, A

3.3 Changes in serum cobalamin by supplementation route and dosage Across 35 comparisons, the mean percentage increase in serum cobalamin following supplementation was approximately 293%, confirming the overall effectiveness of vitamin B12 interventions (Supplementary Table S4)

Whilst this represents off-label use requiring specialist supervision, emerging evidence suggests these medications may offer additional support for carefully selected individuals

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