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NAC protects alveolar type II cells against injury induced by cigarette smoke in knockout mice lacking the nuclear factor erythroid 2-related factor-2 (Nrf2), which is a redox-sensitive transcription factor and is a key regulator of the antioxidant defense system

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Many studies showed LUTS are prevalent in aging and major chronic diseases, including obesity, metabolic syndrome, diabetes, cardiovascular disease, hypertension, obstructive sleep apnea, autoimmune diseases, Alzheimers disease, and Parkinsons disease