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Among these, cholesterol metabolism plays a context-dependent role in ferroptosis, with cholesterol and its intermediates either promoting or suppressing ferroptotic cell death depending on cellular and microenvironmental conditions

The ratiometric readout of RT only responds to GSH (10 mM), but not to glycine (10 mM), cysteine (100 M) or a series of ROS/RNS (100 M)

Kinetic data of the herein presented jr PPO1 mutant Leu244Arg demonstrate that Arg at the 2 nd activity controller position does not convert a TYR into a CO either

Luecke-Johansson S, Gralla M, Rundqvist H, Ho JC, Johnson RS, Gradin K, Poellinger L (2017) A molecular mechanism to switch the aryl hydrocarbon receptor from a transcription factor to an E3 ubiquitin ligase

AD, Atopic dermatitis