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These are called circumventricular organs (CVOs)

Critically, adequate energy substrate utilization is essential for achieving optimal brain growth and maturation

Record retention and archival All the study documents including participants source data and documents will be archived by the study sites after the completion of the study, until the time the sponsor informs in writing to the study sites that they no longer need to maintain the study documents

Therefore, targeting cellular oxidative stress through antioxidants has been suggested as a potential therapeutic option against neurological disorders, particularly using natural plant extracts

On this basis, this review comprehensively examines the role of ferroptosis in NDDs and explores the mechanisms through which exercise modulates ferroptosis to alleviate NDD pathology, thereby providing a scientific foundation for exercise-based brain health interventions