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The Ato/cabo@PEG-TK-PLGA system, administered via dual transdermal and intravenous routes, targeted MDSCs through localized hydrogen peroxide (H2O2)-triggered release of atovaquone and cabozantinib

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Pediatr Cardiol

The foundational obesity finding comes from Kraus and colleagues (Nature, 2014), who showed that knocking down NNMT protected mice against diet-induced obesity establishing NNMT as a metabolic target in the first place