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doi: 10.2147/CLEP.S37505 29

More notably, bilirubin's regulation of ferroptosisby alleviating iron deposition and activating the Nrf-2 pathwayenhances the cellular antioxidant defense system and reduces programmed death of DA neurons under stress conditions ( Secondly, this study proposes a forward-looking perspective: bilirubin's protective effects may extend to the developmental stage of DA neurons during embryogenesis

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Cryopreserved samples from 3 additional healthy controls and 3 additional patients that could not be analyzed fresh were also included in the study after confirming that ROS and glutathione levels in cryopreserved samples fell within the value range of fresh control and patient samples

If you dose at 7am and don't eat until noon, you're wasting the therapeutic window