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A reduction in size, number and function of mitochondria is associated with aging, and supporting mitochondria with essential nutrients like B12 and NAD can potentially slow and even reverse the aging process
Subsequently, we applied a focused refinement approach on the particles used in the reconstruction of holo-complex to improve the resolution for c-MET I and HGF I, resulting in a new cryo-EM map with resolution improved to 4.5 , which allowed us to build reliable models for the K3 and K4 domains of HGF (Supplementary Figs